Pregnancies compromised by disease, trauma, substance abuse, and other factors are not uncommon. They clearly demand special attention from the obstetrician, obstetric nurse, primary care physician and others. Through three successful editions, Queenan has provided these audiences with a concise yet complete guide to managing pregnant patients and fetuses at risk.

For the fourth edition, Dr Queenan has proposed replacing up to a third of the 96 contributors to get some "new blood" into the book. He has invited more contributions from European authors in order to better cater to an international readership. The book will, however, retain the popular "protocols" theme, in which very brief chapters on the spectrum of HRP topics provide quick summaries of a problem and diagnostic and therapeutic steps to manage it. Every chapter will be revised carefully to reflect the latest thinking on the best approach to pregnant patients with risks like tuberculosis, STDs, bleeding, pre-eclampsia, etc. The many quick reference tables and charts will be updates as, of course, will the brief bibliographies accompanying each chapter.

This new edition will provide increased coverage of IUGR, Pre-eclampsia, teratology and genetics. New chapters will be introduced on doppler ultrasound, nuchal translucency and also on AIDS in pregnancy.

Furthermore the fourth edition will be evidence-based. The new editor, Catherine Spong, is a guru of evidence-based medicine and as well as her role as one of the editors of the American journal: Obstetrics and Gynaecology, controls the foetal medicine programme at the National Institute of Health in Washington.

Part 1: Hazards to Pregnancy: 1: Alcohol; 2: Drug Addiction; 3: Teratogens; 4: Smoking; 5: Ionizing Radiation; 6: Microwaves and Ultrasound; 7: Exercise; Part 2: Antenatal Testing: 8: Routine Antenatal Laboratory Tests; 9: Assessment of Gestational Age; 10: a-Fetoprotein Screening for Neural Tube Defects; 11: Tiple Screening for Aneuploidy; 12: Ultrasound Fetal Survey; 13: Amniotic Fluid Indices of Maturity; 14: Clinical Use of Doppler; 15: Fetal Echocardiography; 16: Biophysical Profile; Part 3: Special Procedures: 17: Chorionic Villus Sampling; 18: Genetic Amniocentesis; 19: Third Trimester Amniocentesis; 20: Fetal Blood Sampling; 21: Intrauterine Transfusion; 22: Induction of Labor; 23: Amnioinfusion for Relief of Cord Compressions; 24: New Genetic Tests; Part 4: Maternal Disease: 25: Sickle-Cell Disease; 26: Autoimmune and Isoimmune Thrombocytopenic Purpura; 27: Autoimmune Disease; 28: Systemic Lupus Erythematosus; 29: Cardiac Disease; 30: Renal Disease; 31: Other Renal Diseases; 32: Obesity; 33: Gestational Diabetes; 34: Diabetes Mellitus; 35: Hypothyroidism; 36: Acute Hepatitis; 37: Asthma; 38:Epilepsy; 39: Hypertension; 40: Immunization; 41: Cytomegalovirus; 42: Herpes Simplex; 43: Influenza; 44: Lyme Disease; 45: HIV; 46: Parvovirus Biq; 47: Syphillis; 48: Rubella; 49: Group B Streptococcus; 50: Taxoplasmosis; 51: Varicella; 52: Tuberculosis; 53: Parasitic Infections; 54: Urinary Tract Infections; 55: Acute Abdominal Pain Due to Nonobstetrical Causes; 56: Mastitis; 57: Antibiotics In Pregnancy; Part 5: Obstetrical Problems: 58: First Trimester Vaginal Bleeding; 59: Incompetant Cervix; 60: Nausea and Vomiting; 61: Syncope; 62: Fetal Malformations; 63: Recurrent Fetal Wastage: Genetic Evaluation; 64: Recurrent Fetal Wastage: Non-Genetic Causes; 65: Blighted Ovum; 66: Missed Abortion and Fetal Death; 67: Oligohydramnios; 68: Polyhydramnios; 69: Preeclampsia; 70: Intrauterine Growth Retardation; 71: Rh and Other Blood Group Immunizations; 72: Early Detection of Preterm Labor; 73: Tocolysis; 74: Premature Rupture of the Membranes; 75: Amnionitis; 76: Third Trimester Bleeding; 77: Amniotic Fluid Embolus; 78: Septic Shock; 79: Neonatal Death: Caring for the Parents; Part 6: Labor and Delivery: 80: Medications in Labor; 81: Intrapartum Fetal Monitoring; 82: Dysfunctional Labor; 83: Breech Delivery; 84: Shoulder Dystocia; 85: Twins; 86: Postdate Pregnancies; 87: Postpartum Hemorrhage; 88: Postpartum Endometritis; 89: Wound Dehiscence; Part 7: Clinical Reference Tables: Appendix A: Commonly Used Ultrasound Measurements; Appendix B: Changes in Laboratory Values During Pregnancy; Appendix C: Evaluation of Fetal Defects and Maternal Disease; Appendix D: Newborn Statistical Analysis

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