Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: RNA Viruses, Seventh Edition covers the latest information on RNA viruses, how they cause disease, how they can cause epidemics and pandemics, new therapeutics and vaccine approaches, as provided in new or extensively revised chapters that reflect these advances in this dynamic field.
Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases.
Covers both basic science and medical features of each virus, emphasizing viruses of medical importance and interest, while also including other viruses in specific cases where more is known about their mechanisms of replication or pathogenesis
Includes two new chapters on SARS - Coronavirus 2 covering both basic science and clinical aspects of CoV2 and COVID-19
Covers human immunodeficiency virus (HIV), rotaviruses, respiratory syncytial virus (RSV), measles virus, and more
Features more than 400 full-color illustrations, including key figures for use as lecture slides
Provides quick, flexible access to current information both in print and in an improved eBook format
Discusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, viral persistence and latency for HIV, and mechanisms of viral oncogenesis for HTLV-1 and HCV
New and forthcoming Field’s Virology volumes, available in print and eBook format:
• Emerging Viruses - 2020
• DNA Viruses - 2021
• RNA Viruses
• Fundamental Virology
Enrich Your eBook Reading Experience
Contributors v
Preface viii
Introduction ix
Rhinoviruses 1
James E. Gern • Ann C. Palmenberg
Hepatoviruses 22
Stanley M. Lemon
Astr oviruses 59
Valerie Cortez • Stacey Schultz-Cherry
Rubella V irus 75
T om C. Hobman
Arteriviruses 104
Ying Fang • Eric J. Snijder • Udeni B. R. Balasuriya
Bornaviridae 131
W. Ian Lipkin • Christiane Herden • Jürgen A. Richt •
Thomas Briese
Rhabdoviridae 161
Sean P . J. Whelan • Louis-Marie Bloyet
Mumps V irus 206
Steven A. Rubin • Linda J. Rennick • W. Paul Duprex
Measles V irus 228
Diane E. Grif fin
Respiratory Syncytial Virus and
Metapneumovirus 267
Ursula J. Buchholz • Larry J. Anderson •
Peter L. Collins • Asuncion Mejias
Orthor eoviruses 318
Terence S. Dermody • John S. L. Parker •
Barbara Sherry
Rotaviruses 362
Sue E. Crawford • Siyuan Ding •
Harry B. Greenberg • Mary K. Estes
Orbiviruses 414
Polly Roy
Hepatitis E Virus 443
Robert LeDesma • Alexander Ploss
Retroviridae 465
Stephen P . Goff • Monica J. Roth
Human T-Cell Leukemia Virus
Types 1 and 2 527
Charles R. M. Bangham • Masao Matsuoka
Human Immunodeficiency
V iruses: Replication 558
Melanie Ott • Eric O. Freed
HIV-1: Pathogenesis, Clinical
Manifestations, and Treatment 618
Eileen P . Scully • Daniel R. Kuritzkes
Nonhuman Lentiviruses 648
Ronald C. Desrosiers • David T. Evans
Foamy V iruses 679
Dirk Lindemann • Ottmar Herchenröder
1
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5
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9
10
11
12
13
14
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18
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20
Contents Severe Acute Respiratory
Syndrome Coronavirus 2
(SARS-CoV-2) 706
Stephen A. Goldstein • Brenda G. Hogue •
Julian L. Leibowitz • Susan R. Weiss
SARS-CoV-2/COVID-19: Clinical
Characteristics, Prevention,
and Treatment 741
John H. Beigel • Timothy M. Uyeki
Index 785
21 22
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