Practical Pharmacology in Rehabilitation: Effect of Medication on Therapy With Web Resource serves as a textbook for students and a reference book for practicing rehabilitation professionals. Rather than discussing pharmacology as it relates to only a limited segment of rehabilitation professions, this text takes an interdisciplinary approach to the effects of medications on rehabilitation patients and assists rehabilitation professionals in designing patient-specific therapy plans based on coexisting disease states.

Practical Pharmacology in Rehabilitation explains the necessary pharmacology and then focuses on the relationship between medications and the rehabilitation process. It offers a proactive approach to educating the patient and caregiver, monitoring the patient for side effects, and modifying therapy plans to provide the most effective and safe therapy for each patient. Written by a clinical pharmacist, a speech-language pathologist, and a physical therapist and athletic trainer, this unique guide helps readers in these ways:

• Optimize rehabilitation sessions with appropriately timed and dosed administration of medication.

• Understand the effects of medication on cognition and learning necessary for accomplishing the tasks of rehabilitation.

• Identify medication-associated issues affecting the rehabilitation progress, such as dysphagia and problems with muscle function.

• Work with patients, caregivers, staff, and physicians to determine appropriate interventions regarding medication use in patients.

In each chapter, Patient Cases based on the authors’ clinical experiences engage readers in understanding how medications can positively or negatively affect the rehabilitation process. Readers will need to consider the role of various medications, drug interactions, and drug intolerances on speech and language, cognition, and ADL and motor functioning as they apply concepts to determine possible solutions to each case. Throughout the text more than 100 easy-to-use tables provide quick access to information, including potential side effects affecting rehabilitation for common medications used in treatment for many conditions and other possible side effects or considerations. Expanded versions of many of these tables are offered as downloadable PDFs in the accompanying web resource. Those tables provide more complete and in-depth coverage by breaking medications down by class, indications, dosage, and potential side effects or interactions.

Practical Pharmacology in Rehabilitation begins by presenting foundational concepts necessary for understanding clinical disease states and the impact of medications used for treatment on rehabilitation. Chapters that follow are grouped by categories of clinical disease covering psychiatric and cognitive disorders, neurologic and movement disorders, chronic pain syndromes and substance abuse disorders, immune system disorders, and common chronic diseases such as diabetes, cardiac disease, thyroid and parathyroid disease, respiratory diseases, gastrointestinal diseases, and dysphagia.

Each chapter begins with a definition of the condition or special population that it focuses on. Chapters are organized to provide an overview of the pathophysiology, pharmacology, mechanism of action, dosing and monitoring for effects, drug and food interactions, side effects and effects on rehabilitation, and the role of various rehabilitation specialists for each disease state. Summaries conclude each chapter to reinforce the important concepts covered. A glossary is included, and terms are boldfaced in the text to denote their inclusion. A medication index, an index of important terms, and an appendix with information on administering medications using iontophoresis and phonophoresis are also included.

With Practical Pharmacology in Rehabilitation, students in rehabilitation and related health care fields can gain essential knowledge to prevent adverse occurrences and medical complications and work with their patients, caregivers, pharmacists, and physicians to optimize rehabilitation and the return to daily living. For rehabilitation professionals, this essential reference provides an integrated understanding of medication use with nonpharmacologic therapies in rehabilitation patients.

Part I: Foundations

Chapter 1. Introduction to Medication Monitoring by the Rehabilitation Therapist

Principles of Pharmacotherapy

Generic Medications

Side Effects of Medications

Special Populations and Medication Risk

Patient Education and Medication Use

Safe and Effective Use of Medications

Summary

Chapter 2. Medication’s Effects on the Nervous System, Muscle Function, and Cognition

Central Nervous System

Peripheral Nervous System

Medication-Induced Movement Disorders

Summary

Chapter 3. Nutrition in the Rehabilitation Patient

Physiology of Nutrition

Incidence, Etiology, and Pathophysiology of Malnutrition

Nutritional Screening, Assessment, and Monitoring

Rehabilitation Considerations

Summary

Part II: Medications Used to Treat Psychiatric and Cognitive Disorders

Chapter 4. Medications Used to Treat Depression and Bipolar Disorder

Depression

Drug Interactions With Antidepressants

Bipolar Disorder

Summary

Chapter 5. Medications Used to Treat Psychosis and Schizophrenia

Psychosis

Agitation

Side Effects Associated With Antipsychotic Agents

Drug Interactions

Role of the Rehabilitation Therapist in Promoting Medication Adherence

Rehabilitation Considerations

Summary

Chapter 6. Medications Used to Treat Delirium, Dementia, and Alzheimer’s Disease

Reversible Cognitive Impairment Caused by Medications

Reversible Cognitive Impairment Caused by Medication-Associated Delirium

Irreversible Cognitive Impairment

Summary

Chapter 7. Medications Used to Treat Anxiety, Anxiety Disorders, and Insomnia

Anxiety Disorders

Insomnia

Summary

Part III: Medications Used to Treat Neurologic and Movement Disorders

Chapter 8. Medications Used to Treat Seizure Disorders

Classification of Seizures

Seizures, Convulsions, and Epilepsy

Summary

Chapter 9. Medications Used to Treat Spasticity and Muscle Spasm

Spasticity

Muscle Spasm

Summary

Chapter 10. Medications Used to Treat Parkinson’s Disease

Parkinson’s Disease

Summary

Chapter 11. Medications Used to Treat Amyotrophic Lateral Sclerosis, Multiple Sclerosis, and Myasthenia Gravis

Amyotrophic Lateral Sclerosis

Multiple Sclerosis

Myasthenia Gravis

Summary

Chapter 12. Medications Used to Treat Other Movement Disorders

Essential Tremor

Subcortical Dementia

Huntington’s Disease

Wilson’s Disease

Restless-Leg Syndrome

Medication-Induced Movement Disorders

Summary

Part IV: Medications Used to Treat Pain and Substance-Use Disorders

Chapter 13. Medications Used to Treat Pain

Classification of Pain

Summary

Chapter 14. Medications Used to Treat Chronic Pain Syndromes

Migraine Headache

Fibromyalgia

Trigeminal Neuralgia

Cancer Pain

Amputation Pain

Central Pain Syndromes

Complex Regional Pain Syndrome

Summary

Chapter 15. Medications Used to Treat Substance-Use Disorders

Definition of Substance-Use Disorder

Alcohol-Abuse Disorders

Drug-Abuse Disorders

Summary

Part V: Medications Used to Treat Disorders of the Immune System

Chapter 16. Medications Used to Treat Infections

Classification of Bacteria

Urinary Tract Infections

Skin and Soft-Tissue Infections

Surgical Wound Infections

Vascular Ulcers and Pressure Ulcers

Diabetic Foot Infections

Pneumonia

Antibiotic-Associated Diarrhea

Control of Infection in the Rehabilitation Center

Summary

Chapter 17. Medications Used to Treat Osteoarthritis, Gout, and Rheumatoid Arthritis

Osteoarthritis

Gout

Rheumatoid Arthritis

Related Rheumatic Diseases

Summary

Chapter 18. Medications Used to Treat Cancer

Definition of Cancer

Summary

Part VI: Medications Used to Treat Chronic Disease

Chapter 19. Medications Used to Treat Hypertension, Congestive Heart Failure, and Cardiac Arrhythmias

Cardiovascular Disease

Hypertension

Congestive Heart Failure

Cardiac Arrhythmias

Summary

Chapter 20. Medications Used to Treat Peripheral Artery Disease, Stroke, and Coronary Heart Disease

Atherosclerosis

Peripheral Artery Disease

Stroke

Coronary Artery Disease

Summary

Chapter 21. Medications Used to Treat Diabetes

Diabetes Mellitus

Diabetic Neuropathy

Summary

Chapter 22. Medications Used to Treat Respiratory Disease

Respiratory System

Chronic Obstructive Pulmonary Disease

Emphysema

Chronic Bronchitis

Asthma

Rehabilitation Considerations for Respiratory Disease

Medication Therapy for Respiratory Disease

Summary

Chapter 23. Medications Used to Treat Thyroid Disease, Parathyroid Disease, and Osteoporosis

Thyroid Disease

Hyperthyroidism

Hypothyroidism

Osteoporosis

Paget’s Disease

Hyperparathyroidism

Hypoparathyroidism

Summary

Chapter 24. Medications Used to Treat Gastrointestinal Disorders

Nausea and Vomiting

Constipation

Irritable Bowel Syndrome

Inflammatory Bowel Disease

Dyspepsia and Disorders Associated With Delayed Gastric Emptying

Eosinophilic Esophagitis

Dysphagia

Rehabilitation Considerations in Medication Review and Patient Education

Summary