Uropathology, 2/e
Ming Zhou, MD, PhD, George Netto, MD
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658 Pages
2 Edition
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  • Find information quickly and easily with a templated, easy-to-reference format and concise, bulleted text.
  • Confirm your diagnoses with high-quality color photographs that demonstrate the classic appearance of each disease.
  • Depend on authoritative information from leading experts in the field.
  • Access the full text online, perform quick searches, and download images at expertconsult.com.

Designed for quick reference and efficient, accurate sign-outs, Uropathology, 2nd Edition, provides superbly illustrated, expert guidance in a time-saving format. This updated volume in the High-Yield Pathology series is highly templated for ease of use, featuring bulleted text, authoritative content, and high-quality images that comprehensively cover both non-neoplastic and neoplastic entities, making it easy to recognize the classic manifestations of urologic diseases and quickly confirm your diagnoses.

Key Features
  • Provides in-depth, bulleted outlines for each entity covering definition, anatomy, and pathology: histology, immunohistochemistry, and differential diagnosis.
  • Features 1,600 high-quality illustrations that include gross, radiographic imaging, microscopic, immunohistochemical, and special stains, providing a comprehensive visual summary of the typical features of each entity.
  • Includes expanded information on tumor staging expertly provided by Dr. Ming Zhou, primary author of the College of American Pathologists cancer protocols.
  • Reflects recent guidelines and protocols including:
    •  Restructured tumor classification and new entities
    • New and modified grading systems for GU cancers
    • New and modified staging criteria for all GU cancers
    • New recommendations for reporting
    • New IHC and molecular markers for diagnosis and prognosis for GU cancers
  • Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices


1. Anatomy and Histology of the Prostate

2. Seminal Vesicle/Ejaculatory Duct

3. Cowper Gland

4. Benign Prostatic Hyperplasia

5. Acute Inflammation of the Prostate

6. Chronic Inflammation of the Prostate

7. Nonspecific Granulomatous Prostatitis

8. Post-Biopsy Granuloma

9. Prostatic Xanthoma

10. Granulomatous Prostatitis of Infectious Etiology

11. Simple Atrophy

12. Cystic Atrophy

13. Postatrophy Hyperplasia

14. Partial Atrophy

15. Adenosis

16. Sclerosing Adenosis

17. Clear Cell Cribriform Hyperplasia

18. Hyperplasia of Mesonephric Remnants

19. Basal Cell Hyperplasia

20. Urothelial Metaplasia

21. Squamous Metaplasia

22. Mucin Cell Metaplasia

23. Neuroendocrine Cells Involving the Prostate

24. Verumontanum Mucosal Gland Hyperplasia

25. Prostatic Infarct


26. High-Grade Prostatic Intraepithelial Neoplasia (HGPIN)

27. Intraductal Carcinoma of the Prostate

28. Prostatic Carcinoma, Usual Variant

29. Prostatic Carcinoma, Atrophic Variant

30. Prostatic Carcinoma, Foamy Gland Variant

31. Prostatic Carcinoma, Pseudohyperplastic Variant

32. Prostatic Carcinoma, Mucinous Variant

33. Prostatic Carcinoma, Microcystic Variant

34. Prostatic Intraepithelial Neoplasia (PIN)-Like Adenocarcinoma

35. Sarcomatoid Carcinoma

36. Pleomorphic Giant Cell Carcinoma of the Prostate

37. Lymphoepithelioma-Like Carcinoma of the Prostate

38. Prostate Carcinoma with Squamous Differentiation

39. Ductal Adenocarcinoma

40. Prostatic Adenocarcinoma with Neuroendocrine Differentiation

41. Well-Differentiated Neuroendocrine Tumor

42. Small Cell Carcinoma, Prostate

43. Prostatic Basal Cell Adenoma

44. Basal Cell Carcinoma of the Prostate

45. Squamous Neoplasms Including Squamous Cell and Adenosquamous Carcinoma

46. Urothelial Carcinoma

47. Prostatic Stromal Tumors of Uncertain Malignant Potential

48. Prostatic Stromal Sarcoma

49. Atypical Glands Suspicious for Prostatic Carcinoma

50. High-Grade Prostatic Intraepithelial Neoplasia with Adjacent Atypical Glands

51. Radiation-Induced Changes

52. Hormonal Ablation-Induced Changes

53. Cryoablation Therapy-Induced Changes

54. Immunohistochemical Work-Up of Prostate Carcinoma

55. Gleason Grading of Prostate Carcinoma

56. Prostate Cancer Staging in Radical Prostatectomy

57. Genetics and Genomics in Prostate Cancer

58. Work-Up of "Vanishing” Cancer in Radical Prostatectomy

59. Nonprostatic Adenocarcinoma Involving the Prostate


60. Anatomy and Histology of Seminal Vesicles

61. Amyloidosis

62. Seminal Vesicle Adenocarcinoma

63. Mixed Epithelial and Stromal Tumor


64. Anatomy and Histology of the Urinary Bladder

65. von Brunn Nests

66. Cystitis Cystica et Glandularis

67. Squamous Metaplasia

68. Intestinal Metaplasia

69. Nephrogenic Metaplasia/Adenoma

70. Polypoid and Papillary Cystitis

71. Follicular Cystitis

72. Giant Cell Cystitis

73. Interstitial Cystitis/Painful Bladder Syndrome

74. Eosinophilic Cystitis

75. Infectious Cystitis

76. Malakoplakia

77. Granulomatous Cystitis After BCG

78. Radiation Cystitis

79. Chemotherapy-Induced Cystitis

80. Endometriosis of the Bladder

81. Bladder Endocervicosis

82. Bladder Exstrophy

83. Urachal Anomaly

84. Bladder Diverticulum

85. Ectopic Prostate Tissue


86. Urothelial Proliferation of Uncertain Malignant Potential

87. Reactive Urothelial Atypia

88. Urothelial Atypia of Unknown Significance

89. Urothelial Dysplasia

90. Urothelial Carcinoma In Situ

91. Urothelial Papilloma

92. Inverted Papilloma

93. Papillary Urothelial Neoplasm of Low Malignant Potential

94. Low-Grade Papillary Urothelial Carcinoma

95. High-Grade Papillary Urothelial Carcinoma

96. Invasive Urothelial Carcinoma

97. Urothelial Carcinoma with Inverted Growth Pattern

98. Urothelial Carcinoma with Squamous Differentiation

99. Urothelial Carcinoma with Villoglandular Differentiation

100. Urothelial Carcinoma, Plasmacytoid Variant

101. Urothelial Carcinoma, Nested Variant

102. Urothelial Carcinoma, Micropapillary Variant

103. Urothelial Carcinoma, Microcystic Variant

104. Urothelial Carcinoma, Lymphoepithelioma- Like Carcinoma Variant

105. Urothelial Carcinoma, Clear Cell (Glycogen-Rich) Variant

106. Lipid-Rich Urothelial Carcinoma

107. Urothelial Carcinoma, Giant Cell Variant

108. Urothelial Carcinoma with Syncytiotrophoblastic Giant Cells

109. Urothelial Carcinoma with Rhabdoid Differentiation

110. Urothelial Carcinoma Similar to Giant Cell Tumor of Bone

111. Undifferentiated Urothelial Carcinomas

112. Small Cell Carcinoma of the Urinary Bladder

113. Urothelial Carcinoma with Unusual Stromal Reactions

114. Urothelial Carcinoma with Sarcomatoid Differentiation

115. Villous Adenoma

116. Adenocarcinoma

117. Clear Cell Adenocarcinoma

118. Urachal Adenocarcinoma

119. Squamous Cell Carcinoma

120. Paraganglioma

121. Staging of Urothelial Carcinoma of the Urinary Bladder and Urethra

122. Molecular Genomics of Bladder Cancer

123. Secondary Spread of Prostate Carcinoma to the Bladder

124. Secondary Adenocarcinoma Involving the Bladder, Other than Prostatic Carcinoma


125. Anatomy of the Kidney

126. Renal Dysplasia

127. Localized Cystic Disease of the Kidney

128. Autosomal Recessive Polycystic Kidney Disease

129. Autosomal Dominant Polycystic Kidney Disease

130. Medullary Sponge Kidney

131. Acquired Cystic Renal Disease

132. Simple Cortical Cyst

133. Acute Pyelonephritis

134. Chronic Nonobstructive Pyelonephritis

135. Chronic Obstructive Pyelonephritis

136. Xanthogranulomatous Pyelonephritis

137. Renal Papillary Necrosis

138. Benign Nephrosclerosis

139. Malignant Nephrosclerosis

140. Acute Kidney Injury (Acute Tubular Necrosis)

141. Acute Interstitial Nephritis

142. Infectious Interstitial Nephritis


143. Papillary Adenoma

144. Renal Oncocytoma

145. Clear Cell Renal Cell Carcinoma

146. Multilocular Cystic Renal Neoplasm of Low Malignant Potential

147. Papillary Renal Cell Carcinoma

148. Chromophobe Renal Cell Carcinoma

149. Fumarate Hydratase-Deficient Renal Cell Carcinoma, Including Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome

150. Collecting Duct Carcinoma

151. Renal Medullary Carcinoma

152. MIT Family Translocation Renal Cell Carcinoma

153. Succinate Dehydrogenase-Deficient Renal Cell Carcinoma

154. Mucinous Tubular and Spindle Cell Carcinoma

155. Tubulocystic Carcinoma

156. Acquired Cystic Kidney Disease-Associated Renal Cell Carcinoma

157. Thyroid-Like Follicular Renal Cell Carcinoma

158. Clear Cell Papillary Renal Cell Carcinoma

159. Renal Cell Carcinoma with Fibromyomatous Stroma

160. Eosinophilic Solid Cystic Renal Cell Carcinoma

161. Renal Cell Carcinoma with Somatic Mutations in TSC/mTORC1 Genes

162. Renal Cell Carcinoma with Sarcomatoid Differentiation

163. Renal Cell Carcinoma, Unclassified Type

164. Grading System for Renal Cell Carcinoma

165. Staging of Renal Cell Carcinoma

166. Renal Cell Carcinoma in von Hippel-Lindau Disease

167. Renal Cell Neoplasms in Birt-Hogg-Dubé (BHD) Syndrome

168. Renal Tumors in Tuberous Sclerosis Complex (TSC)

169. Metanephric Adenoma

170. Metanephric Stromal Tumor

171. Wilms Tumor

172. Nephrogenic Rests and Nephroblastomatosis

173. Congenital Mesoblastic Nephroma (CMN)

174. Rhabdoid Tumor of the Kidney

175. Clear Cell Sarcoma of the Kidney

176. Ossifying Renal Tumor of Infancy

177. Renal Angiomyolipoma

178. Epithelioid Angiomyolipoma

179. Juxtaglomerular Cell Tumor

180. Renal Medullary Fibroma (Renomedullary Interstitial Cell Tumor)

181. Mixed Epithelial and Stromal Tumor Family

182. Primary Renal Synovial Sarcoma

183. Renal Carcinoid Tumor


184. Ureteropelvic Junction Obstruction

185. Idiopathic Retroperitoneal Fibrosis, Including IgG4-Related Disease

186. Fibroepithelial Polyp of the Ureter and Renal Pelvis

187. Ureteral Urothelial Carcinoma and Staging

188. Staging for Pelvic Urothelial Carcinoma


189. Testis: Anatomy and Histology

190. Cryptorchidism

191. Testiculosplenic Fusion

192. Adrenal Cortical Rests

193. Spermatic Cord Torsion and Testicular Infarction

194. Testicular Microlithiasis

195. Vasculitis

196. Male Infertility Workup

197. Maturation Arrest

198. Hypospermatogenesis

199. Germ Cell Aplasia, Sertoli Cell-only Syndrome

200. Excurrent Duct Obstruction

201. Pre-pubertal Gonadotropin Deficiency

202. Postpubertal Gonadotrophin Deficiency

203. Viral Orchitis

204. Granulomatous Orchiepididymitis

205. Nonspecific Granulomatous Orchitis

206. Androgen Insensitivity Syndrome

207. Klinefelter Syndrome

208. Testicular Tumor of the Adrenogenital Syndrome

209. Embryonic Testicular Regression (Vanishing Testis Syndrome)

210. Gonadal Dysgenesis


211. Germ Cell Neoplasia In Situ

212. Specific Forms of Intratubular Germ Cell Neoplasia

213. Seminoma

214. Embryonal Carcinoma

215. Postpubertal-Type Yolk Sac Tumor

216. Postpubertal-Type Teratoma

217. Mixed Germ Cell Tumor

218. Teratoma with Somatic-Type Malignancies

219. Choriocarcinoma

220. Non-Choriocarcinomatous Trophoblastic Tumors

221. Regressed Germ Cell Tumors

222. Spermatocytic Tumor

223. Prepubertal-Type Teratoma, Testicular Carcinoid Tumor

224. Teratoma, Prepubertal-Type, Dermoid Cyst

225. Prepubertal Teratoma, Epidermoid Cyst

226. Yolk Sac Tumor, Prepubertal Type

227. Leydig Cell Tumor

228. Sertoli Cell Tumor

229. Sclerosing Sertoli Cell Tumor

230. Large Cell Calcifying Sertoli Cell Tumor

231. Adult Granulosa Cell Tumor

232. Juvenile Granulosa Cell Tumor

233. Fibrothecoma

234. Stromal Tumor of the Testis, Mixed and Unclassified Type

235. Myoid Gonadal Stromal Tumor

236. Gonadoblastoma

237. Testicular Lymphoma

238. Ovarian Epithelial-Type Testicular Tumors

239. Tumors of the Rete Testis

240. Testicular Cancer Staging


241. Appendix Testis

242. Appendix Epididymis

243. Glandular Inclusions in Inguinal Herniorrhaphy Specimens

244. Hydrocele

245. Spermatocele

246. Vasitis Nodosa

247. Sperm Granuloma

248. Adenomatoid Tumor

249. Fibrous Pseudotumor

250. Paratesticular Idiopathic Smooth Muscle Hyperplasia

251. Papillary Cystadenoma of the Epididymis

252. Paratesticular Lipoma

253. Paratesticular Liposarcoma

254. Paratesticular Rhabdomyosarcoma

255. Leiomyoma of the Spermatic Cord and Testicular Adnexa

256. Paratesticular Leiomyosarcoma

257. Aggressive Angiomyxoma of the Male Genital Region

258. Cellular Angiofibroma

259. Malignant Mesothelioma, Paratesticular

260. Epithelial Tumors of the Rete Testis


261. Fibroepithelial Polyp of the Urethra

262. Urethral Caruncle

263. Urethral Diverticulum

264. Urethral Stricture

265. Polypoid Urethritis

266. Condyloma Acuminatum

267. Prostatic-Type Urethral Polyp

268. Urethral Urothelial Carcinoma Associated with Bladder Urothelial Carcinoma

269. Primary Urethral Carcinoma

270. Urethral Adenocarcinoma

271. Clear Cell Adenocarcinoma of the Urethra

272. Zoon Balanitis

273. Lichen Sclerosus et Atrophicus (Balanitis Xerotica Obliterans)

274. Pseudoepitheliomatous Keratotic Micaceous Balanitis

275. Peyronie Disease

276. Squamous Hyperplasia of the Penis

277. Penile Intraepithelial Neoplasia (PeIN)

278. Differentiated Penile Intraepithelial Neoplasia

279. Squamous Cell Carcinoma of the Penis, Usual Type

280. Basaloid Squamous Cell Carcinoma

281. Squamous Cell Carcinoma, Papillary- Basaloid

282. Penile Warty (Condylomatous) Carcinoma

283. Squamous Cell Carcinoma, Warty-Basaloid

284. Clear Cell Squamous Cell Carcinoma

285. Lymphoepithelioma-Like Carcinoma

286. Squamous Cell Carcinoma, Verrucous

287. Squamous Cell Carcinoma, Papillary

288. Squamous Cell Carcinoma, Pseudohyperplastic Variant

289. Squamous Cell Carcinoma, Pseudoglandular

290. Squamous Cell Carcinoma, Cuniculatum

291. Sarcomatoid (Spindle Cell) Squamous Cell Carcinoma of the Penis

292. Adenosquamous Carcinoma of the Penis

293. Mixed Squamous Cell Carcinoma of the Penis

294. Penile Basal Cell Carcinoma

295. Extramammary Paget Disease of the Penis and Scrotum

296. Merkel Cell Carcinoma of the Genitourinary Tract

297. Sclerosing Lipogranuloma

298. Idiopathic Scrotal Calcinosis

299. Genital Melanosis and Lentiginosis

300. Mucosal Melanoma of the Genitourinary System

301. Staging for Penile Squamous Cell Carcinoma

302. Staging for Urethral Carcinoma


303. Inflammatory Myofibroblastic Tumor of the Bladder

304. Leiomyoma of the Bladder

305. Leiomyosarcoma of the Bladder

306. Solitary Fibrous Tumor

307. Gastrointestinal Stromal Tumor of the Genitourinary Tract

308. Lymphomas of the Genitourinary Organs


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