CONTENTS
Contributors iii
Foreword ix
Preface for the Fifth Edition x
Acknowledgments xi
SECTION I: Basics of Healthcare Epidemiology and Infection Prevention
CHAPTER 1 Principles of Healthcare Epidemiology 1
FRANCES J. BOLY, VICTORIA J. FRASER, AND JENNIE H. KWON
CHAPTER 2 Infectious Disease Surveillance in Healthcare Settings 21
EMILY E. SICKBERT-BENNETT AND LAUREN M. DIBIASE
CHAPTER 3 Isolation of Patients With Communicable Diseases 30
JASON BOWLING AND JAN PATTERSON
CHAPTER 4 Hand Hygiene 53
ELI N. PERENCEVICH AND ALEXANDRE R. MARRA
CHAPTER 5 Role of the Microbiology Laboratory and Molecular Diagnostics in
Healthcare Epidemiology and Infection Prevention 69
KAEDE V. SULLIVAN AND DANIEL J. DIEKEMA
CHAPTER 6 Legal Issues in Healthcare Epidemiology and Infection Prevention 81
SARAH M. FOTHERINGHAM
CHAPTER 7 Ethical Issues in Healthcare Epidemiology and Infection Prevention 91
EMILY LANDON AND CASSANDRA OEHLER
SECTION II: Tools/Skills for the Modern Healthcare Epidemiologist
CHAPTER 8 Quality Improvement for Healthcare Epidemiology: Creating
a Culture of Excellence 97
JULIA E. SZYMCZAK
CHAPTER 9 Investigation of Outbreaks 105
ERICA S. SHENOY
CHAPTER 10 Developing an Infection Prevention Program 119
MARY ELLEN SCALES, JACOB SMITH, AND SARAH HAESSLER
CHAPTER 11 Communication and Messaging Strategies in Infection Prevention 127
LOUISE-MARIE DEMBRY AND ANN FREELAND FISHERSECTION III: Epidemiology and Prevention of Healthcare-Associated Infections
CHAPTER 12 Healthcare-Associated Infections Related to the Use of Intravascular Devices 139
D. ALEXANDER PERRY AND PAYAL K. PATEL
CHAPTER 13 Healthcare-Associated Bloodstream Infections 153
RICHARD J. HANKINS AND MARK E. RUPP
CHAPTER 14 Healthcare-Associated Urinary Tract Infections (Including CAUTI) 169
SONALI D. ADVANI AND MOHAMAD G. FAKIH
CHAPTER 15 Surgical Site Infections 183
JESSICA L. SEIDELMAN, SARAH S. LEWIS, ARTHUR W. BAKER, AND DEVERICK J. ANDERSON
CHAPTER 16 Hospital-Acquired Pneumonia and Ventilator-Associated Events 198
MICHAEL KLOMPAS
CHAPTER 17 Clostridioides (Clostridium) difficile 216
LARRY K. KOCIOLEK AND ERIK R. DUBBERKE
CHAPTER 18 Healthcare-Associated Gastrointestinal Illness 227
SHANNON J. KOH AND TRISH M. PERL
CHAPTER 19 MDRO Infections: Gram-Positive Organisms (Including Methicillin-
Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococcus) 243
SARAH E. SANSOM AND MARY K. HAYDEN
CHAPTER 20 MDRO Infections: Gram-Negative Organisms 286
JOHN P . MILLS, OWEN R. ALBIN, LARAINE WASHER, LONA MODY, AND KEITH S. KAYE
CHAPTER 21 Healthcare-Associated Fungal Infections (Candida and Invasive Molds) 306
KAITLIN FORSBERG, KARLYN D. BEER, BRENDAN JACKSON, AND TOM CHILLER
CHAPTER 22 Healthcare-Associated Viral Respiratory Infections 318
JULIA S. SAMMONS AND LORI K. HANDY
CHAPTER 23 Mycobacterium tuberculosis 325
MARCOS C. SCHECHTER AND SUSAN M. RAY
CHAPTER 24 Nontuberculous Mycobacteria 347
KATIA CAMILLE HALABI AND LISA SAIMAN
CHAPTER 25 Epidemiology and Prevention of Healthcare-Associated Infections
Related to Animals in the Hospital 358
MICHAEL BEN-ADERET AND REKHA K. MURTHY
SECTION IV: Epidemiology and Prevention of Healthcare-Associated Infections in
Special Patient Populations and Healthcare Settings
CHAPTER 26 Healthcare-Associated Infections in Obstetric Patients 368
AMANDA L. AGARD AND AMY B. KRESSELCHAPTER 27 Healthcare-Associated Infections in Burn Patients 378
HAYLEY ELISABETH CUNNINGHAM, DAVID VAN DUIN, AND ANNE MONICA LACHIEWICZ
CHAPTER 28 Healthcare-Associated Eye Infections 401
MARLENE L. DURAND AND TERESA C. CHEN
CHAPTER 29 Infection Prevention Issues Unique to Newborns
and the Neonatal Intensive Care Unit 410
MATTHEW LINAM AND OMAYMA AMIN
CHAPTER 30 Infection Prevention and Control in Hematopoietic Stem Cell Transplant
and Oncology Patients 427
ALEXANDRE E. MALEK AND ISSAM I. RAAD
CHAPTER 31 Healthcare-Associated Infections in Solid Organ Transplant Recipients 440
DAVID P . CALFEE
CHAPTER 32 Epidemiology and Prevention of Infections in Long-term Care Facilities 455
SUZANNE F . BRADLEY
CHAPTER 33 Infection Prevention and Control in Resource-Limited Settings 470
ANUCHA APISARNTHANARAK, ANUCHA THATRIMONTRICHAI, AND LINDA M. MUNDY
SECTION V: Infections Related to Diagnostic and Therapeutic Procedures
CHAPTER 34 Healthcare-Associated Infections in Anesthesia 480
JOSHUA K. SCHAFFZIN AND L. SILVIA MUNOZ-PRICE
CHAPTER 35 Dialysis-Associated Infections 490
SHANNON A. NOVOSAD, MATTHEW J. ARDUINO, AND PRITI R. PATEL
SECTION VI: Epidemiology and Prevention of Healthcare-Associated Infections
in Healthcare Workers
CHAPTER 36 Developing an Occupational Infection Prevention Program 516
MARK RUSSI
CHAPTER 37 Vaccination of Healthcare Personnel 524
KAP SUM FOONG AND HILARY M. BABCOCK
CHAPTER 38 Exposures to Blood-Borne Pathogens 546
SUSAN E. BEEKMANN AND DAVID K. HENDERSON
CHAPTER 39 Exposures to Contagious Infectious Diseases 581
ELIZABETH A. SODA AND DAVID T. KUHAR
SECTION VII: Prevention of Healthcare-Associated Infections Related to the Hospital
Environment, Sterilization, and Disinfection
CHAPTER 40 High-Level Disinfection and Sterilization 589
WILLIAM A. RUTALA AND DAVID J. WEBERCHAPTER 41 Prevention of Infections Related to Construction, Renovation,
and Demolition in Healthcare Facilities 611
RUSSELL N. OLMSTED
CHAPTER 42 Infection Prevention and the Physical Environment 626
CURTIS J. DONSKEY
CHAPTER 43 Prevention of Waterborne Infections (Including Legionella) 638
MARTHA L. CARVOUR AND LOREEN HERWALDT
SECTION VIII: Reducing Antimicrobial Resistance in Healthcare Settings
Through Antimicrobial Stewardship
CHAPTER 44 Developing an Antimicrobial Stewardship Program in the Hospital Setting 647
VALERIA FABRE, SARA E. COSGROVE, AND EMILY S. SPIVAK
CHAPTER 45 Interventions to Optimize Antimicrobial Use 660
EDWARD STENEHJEM, RACHEL FOSTER, NICK TINKER, AND BRANDON WEBB
CHAPTER 46 Antibiotic Stewardship in Long-term Care Settings 671
PHILIP D. SLOANE, MEERA TANDAN, KIMBERLY WARD, AND SHERYL ZIMMERMAN
CHAPTER 47 Antimicrobial Stewardship in Outpatients 685
ZACHARY WILLIS AND EMILY CICCONE
SECTION IX: Emergency Preparedness
CHAPTER 48 Developing an Emergency Preparedness Program 693
ANGELA HEWLETT, SHELLY SCHWEDHELM, AND PAUL BIDDINGER
CHAPTER 49 Emergency Preparedness: Highly Communicable Respiratory Infections 704
WALTER ZINGG AND HANAN H. BALKHY
CHAPTER 50 Emergency Preparedness: Highly Communicable Infections
Transmitted by Contact 712
DAVID J. WEBER
Index 727
