Contributors viii
Preface to the First Edition x
Preface to the Second Edition xi
Preface to the Third Edition xii
Part 1: Evolution of Biological Concepts 1
1 Biological Basis of Orthodontic Tooth Movement: A Historical Perspective 3
Vinod Krishnan and Ze’ev Davidovitch
2 Biology of Orthodontic Tooth Movement: The Evolution of Hypotheses and Concepts 16
Vinod Krishnan and Ze’ev Davidovitch
Part 2: Mechanics Meets Biology 33
3 Cellular and Molecular Biology of Orthodontic Tooth Movemen 35
Jaap C. Maltha, Vinod Krishnan, and Anne Marie Kuijpers-Jagtman
4 Inflammatory Response in the Periodontal Ligament and Dental Pulp During Orthodontic Tooth Movement 49
Masaru Yamaguchi and Gustavo Pompermaier Garlet
5 The Effects of Mechanical Loading on Hard and Soft Tissues and Cells 68
Itzhak Binderman, Nasser Gadban, and Avinoam Yaffe
6 Biological Aspects of Bone Growth and Metabolism in Orthodontics 77
James K. Hartsfield, Jr., Priyanka Gudsoorkar, Lorri A. Morford, and W. Eugene Roberts, Jr.
7 Mechanical Load, Sex Hormones, and Bone Modeling 100
Sara H. Windahl and Ulf H. Lerner
8 Biological Reactions to Temporary Anchorage Devices 117
Gang Wu, Jiangyue Wang, Ding Bai, Jing Guo, Haikun Hu, and Vincent Everts
9 Tissue Reaction to Orthodontic Force Systems. Are we in Control? 129
Birte Melsen, Michel Dalstra, and Paolo M. Cattaneo
Part 3: Inflammation and Orthodontics 139
10 The Influence of Orthodontic Treatment on Oral Microbiology 141
Alessandra Lucchese and Lars Bondemark
11 Markers of Paradental Tissue Remodeling in the Gingival Crevicular Fluid and Saliva of Orthodontic Patients 159
Taylor E. Glovsky and Laura R. Iwasaki
Part 4: Personalized Diagnosis and Treatment 169
12 Genetic Influences on Orthodontic Tooth Movement 171
Margarita Zeichner-David
13 Precision Orthodontics: Limitations and Possibilities in Practice 189
James K. Hartsfield, Jr., Priyanka Gudsoorkar, and Lorri A. Morford
14 The Effect of Drugs, Hormones, and Diet on Orthodontic Tooth Movement 199
Vinod Krishnan, James J. Zahrowski, and Ze’ev Davidovitch
Part 5: Rapid Orthodontics 217
15 Biological Orthodontics: Methods to Accelerate or Decelerate Orthodontic Tooth Movement 219
Vinod Krishnan, Ze’ev Davidovitch, and Anne Marie Kuijpers-Jagtman
16 Surgically Assisted Tooth Movement: Biological Application 238
Carlalberta Verna, Raffaele Spena, Michel Dalstra, Paolo M. Cattaneo, and Judith V. Ball
17 Precision Accelerated Orthodontics: How Micro-osteoperforations and Vibration Trigger Inflammation to Optimize Tooth Movement 265
Mani Alikhani, Jeanne M. Nervina, and Christina C. Teixeira
Part 6: Long-term Effects of Tooth-moving Forces 277
18 Mechanical and Biological Determinants of Iatrogenic Injuries in Orthodontics 279
Vinod Krishnan, Ambili Renjithkumar, and Ze’ev Davidovitch
19 The Biological Background of Relapse of Orthodontic Tooth Movement 297
Jaap C. Maltha, Vaska Vandevska-Radunovic, and Anne Marie Kuijpers-Jagtman
Part 7: Tooth-movement Research 309
20 Planning and Executing Tooth-movement Research 311
Vinod Krishnan, Ze’ev Davidovitch, and Rajesh Ramachandran
21 Controversies and Research Directions in Tooth-movement Research 327
Vinod Krishnan, Anne Marie Kuijpers-Jagtman, and Ze’ev Davidovitch
Index 343
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