Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You'll also have easy access to the complete contents and illustrations online at expertconsult.com.
Key Features
Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field.
Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation.
New to This Edition
Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more.
Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease.
Access the complete contents and illustrations online at expertconsult.com - fully searchable!
II. Embryology: Embryology . Regulation of Embryogenesis . Pathophysiology of Congenital Malformations
III. The Placenta: Placental Development . Regulation of the Placental Circulation . Mechanisms of Transfer Across the Human Placenta . Endocrine and Paracrine Function of the Human Placenta . Placental Proteins . Placental Separation at Birth . Multiple Pregnancy
IV. Developmental Pharmacology and Pharmacokinetics: Basic Pharmacologic Principles . Basic Pharmacokinetic Principles . Physiochemical and Structural Properties Regulating Placental Drug Transfer . Genetic Regulation of Drug Metabolism . Drug Distribution During Fetal Life . Drug Protein Binding During Development . Development of Renal Excretion of Drugs During Ontogeny . Pharmacodynamics and Receptor Sensitivity During Development . Drug Abuse During Fetal and Neonatal Life . Sympathoadrenal Mechanisms During Development . Developmental Neuropharmacology . Physiologic Differences of Clinical Significance . Therapeutic Drug Monitoring in the Newborn . Drug Excretion during Lactation
V.Intrauterine Growth: Intrauterine Growth and Nutrition
VI. Postnatal Growth and Nutrition: Infant Growth in the First Year of Life . Endocrine and Other Factors Affecting Growth . Water Requirements . Energy Requirements . Protein Requirements . Carbohydrate Requirements . Fat Metabolism and Requirements . Mineral and Trace Element Requirements . Vitamin Requirements . Human Milk Composition and Function in the Infant . Types and Methods of Feeding for Infants . Nutritional Assessment . Growth Outcome of Critically Ill Neonates
VII. Perinatal Iron, Trace Minerals, and Vitamin Metabolism: Iron Metabolism during Fetal and Neonatal Life . Trace Element Metabolism in the Fetus and Neonate . Metabolism of Vitamin A and Water Soluble Vitamins During Fetal and Neonatal Life . Vitamin E Metabolism in the Fetus and Neonate . Vitamin K Metabolism during the Fetal and Neonatal Periods
VIII. Lipid Metabolism in the Fetus and Newborn: Placental Transport of Free Fatty Acids, Glycerol, and Ketone Bodies . Lipid Accretion in the Fetus and Newborn . Brown Adipose Tissue: Development and Function . Lipids and an Energy Source for the Premature and Full-Term Neonate . Ketone Body Production and Metabolism in the Fetus and Newborn . Very Long Chain Fatty Acids in the Developing Retina and Brain . Physiological Effects of Lipid Infusions . Developmental Physiology of Lipoproteins and Cholesterol . Lipoprotein Lipase
IX. Carbohydrate Metabolism: Metabolism of Glucose and Methods of Investigation in the Fetus and Newborn . Maternal Metabolism During Pregnancy . Carbohydrate Metabolism in the Fetus . Role of Glucoregulatory Hormones on Hepatic Glucose Metabolism During the Perinatal Period . Cell Glucose Transport and Glucose Handling During Fetal and Neonatal Development . Glucose Metabolism During the Transition to Postnatal Life . Hypoglycemia and Hyperglycemia in the Newborn
X. Protein Metabolism: General Concepts of Protein Metabolism . Fetal Requirements and Placental Transfer of Nitrogenous Compounds . Nitrogen Sources for the Newborn . Protein Metabolism in the Newborn . Protein and Amino Acid Requirements . Modification of Protein Metabolism Because of Disease
XI. Thermoregulation: Perinatal Thermal Physiology . Neonatal Thermal Physiology . Physics and Physiology of Human Incubation . Temperature Measurement in the Preterm Newborn . Incubator Management
XII. Skin: Structural and Biochemical Organogenesis of Skin and Cutaneous Appendages in the Fetus and Newborn . Development of the Cutaneous Circulation . Composition of Skin Lipids . Sweating in the Neonate . pH Patterns in Newborn Skin . Skin Barrier Function . Bacterial Colonization of the Skin of the Newborn
XIII. Fetal and Neonatal Cardiovascular Physiology: Development of the Fetal Heart . Molecular Development of the Heart . Role of Peptide Growth Factors in Cardiovascular Development . Fetal and Neonatal Cardiovascular Physiologic Development . Developmental Electrophysiology in the Fetus and Neonate . Developmental Biology of the Pulmonary Vasculature . Development of the Pulmonary Circulation: Metabolic Aspects . Development of the Gastrointestinal Circulation in the Fetus and Newborn . Regulation of the Fetal Cerebral Circulation . Autonomic and Central Neuroregulation of Fetal Cardiovascular Function . Endocrine Regulation of the Fetal Circulation . Nitric Oxide and the Perinatal Circulation . Regulation of Umbilical Blood Flow . Fetal and Placental Circulation During Labor . Cardiovascular Diagnosis in the Fetus and the Effects of Congenital Heart Lesions on Developing Physiology . Response of the Fetal Circulation to Stress . Fetal and Neonatal Congestive Heart Failure . Physiology of Resuscitation
XIV. The Lung: Normal and Abnormal Structural Development of the Lung . Fetal and Neonatal Lung-liquid Balance . Functional Development of the Upper Airway . Functional Development of the Lower Airway . Functional Development of Respiratory Muscles . Mechanics of Breathing . Pulmonary Gas Exchange in the Developing Lung . Oxygen Transport and Delivery . Control of Breathing in Fetal Life and Onset and Control of Breathing in the Neonate . Pathophysiology of Apnea of Prematurity . Evaluation of Pulmonary Function in the Neonate . Pathophysiology of Hyaline Membrane Disease (Excluding Surfactant) . Pathophysiology of Lung Injury and Repair: Special Features of the Immature Lung . Pathophysiology of Chronic Lung Disease . Physiologic Effects of Conventional Mechanical Ventilation . Physiology of High Frequency Ventilation . Liquid Ventilation . Physiology of Extracorporeal Membrane Oxygenation
XV. Pulmonary Surfactant: Historical Perspective . Composition of Pulmonary Surfactant Lipids and Proteins . Biophysical Activities of Pulmonary Surfactant . Lung Morphogenesis: Formation and Function of the Alveolar Surface Layer . Regulation of Surfactant-associated Phospholipid Synthesis and Secretion . Pathophysiology of Respiratory Distress Syndrome . Hormonal Therapy for Prevention of Respiratory Distress Syndrome . Surfactant Replacement Therapy
XVI. Physiology Of The Gastrointestinal Tract in the Fetus and Neonate: Cellular and Molecular Aspects of Human Gastrointestinal Development . Organogenesis, Innervation, and Histologic Development of the Gastrointestinal Tract . Development of the Enteric Nervous System . Development of Gastric Secretory Function . Development of Intestinal and Colonic Motility . Motility of the Upper Gastrointestinal Tract in the Fetus and Neonate . Development of Exocrine Pancreatic Function . Digestive and Absorptive Function in the Fetus and Infant . Pathophysiology of Gastroesophageal Reflux . Pathophysiology and Epidemiology of Necrotizing Enterocolitis
XVII. Liver and Bilirubin Metabolism: Organogenesis and Histologic Development of the Liver . Fetal and Postnatal Hepatic Vasculature and Blood Flow . Bile Acid Metabolism during Development . Bile Secretion and its Control in the Mature and Immature Organism . Hepatic Disposition of Xenobiotics during Prenatal and Early Postnatal Development . Bilirubin Metabolism and Toxicity in the Newborn . Pathophysiology of Breast-Milk Jaundice . Phototherapy for Neonatal Jaundice . Pathophysiology of Metabolic Diseases of the Liver . Pathogenesis of Neonatal Cholestasis . Evaluation of Liver Function
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참고
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(10881) 경기도 파주시 회동길 338 (서패동 474-1) 군자출판사빌딩 4층
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