Clinical Dilemmas in Diabetes answers the clinical questions commonly encountered when diagnosing, treating, and managing patients with diabetes and its associated complications. Designed to support informed, evidence-based care, this authoritative clinical guide includes contributions from leading endocrinologists and diabetes researchers that discuss a diverse range of recent developments. Concise and focused chapters cover prediabetes, diabetes diagnosis, initial evaluation and management, disease complications, and cardiovascular disease and risk factors.

Now in its second edition, Clinical Dilemmas in Diabetes contains extensively reviewed and revised information throughout. New and updated chapters examine prediction, diagnosis, and management of early Type 1 diabetes, ophthalmic complications, screening asymptomatic patients for cardiovascular disease, new agents for treatment of dyslipidemia, closed loop systems in Type 1 diabetes, upper gastrointestinal manifestations, managing hyperglycemia in critically ill patients, and more. Edited by Dr. Vella at the Mayo Clinic, this highly practical resource:

• Encourages evidence-based clinical decision-making, rather than algorithm-based approaches
• Provides clear guidance on common problematic areas, especially in cases where conflicts in treatment for the disease and the complications occur
• Emphasizes the importance of translating the results of clinical trials to individual care and management of diabetes
• Contains effective learning and revision tools, including Learning Points, chapter introductions and summaries, tables and figures, color diagrams and charts, and full references

Part of the popular Clinical Dilemmas series, Clinical Dilemmas in Diabetes is a must-have guide for anyone involved in the treatment of patients with diabetes, particularly endocrinologists, diabetes specialists and consultants, cardiologists, residents, fellows, specialist nurses, and general practitioners with an interest in diabetes.

Contributors

Preface

Part I Prediabetes and the Diagnosis of Diabetes

1 Is prediabetes a risk factor or is it a disease?
Jacob Kohlenberg and Adrian Vella

2 Prediction, early diagnosis and appropriate management of early type 1 diabetes including disease-modifying therapy

3 Reclassifying or Declassifying Diabetes? Can Clinical Characteristics Guide Classification & Treatment?
Adrian Vella

4 How should secondary causes of diabetes be excluded?
Tomás P. Griffin, Aonghus O’Loughlin and Sean F. Dinneen

5 How to screen appropriately for Monogenic Diabetes
Adrian Vella

PART II Initial Evaluation and Management of Diabetes

6 Managing Gestational Diabetes During and After Pregnancy
Aoife M Egan, Fidelma P Dunne

7 What is the role of self-monitoring in diabetes? Is there a role for postprandial glucose monitoring? How does continuous glucose monitoring integrate into clinical practice?
Rami Almokayyad and Robert Cuddihy

8 Is HbA1c the most important therapeutic target in the outpatient management of diabetes?
Kristin Gonzales and Steven A. Smith

9 Closed loop systems in type 1 diabetes

10 Optimizing diet in patients with diabetes
Meera Shah

11 Insulin sensitizers versus secretagogues as first-line therapy for diabetes: Rationale for clinical choice
Robert J. Richards, L. Yvonne Melendez-Ramirez, and William T. Cefalu

12 Are insulin sensitizers useful additions to insulin therapy?
John W. Richard III and Philip Raskin

13 Incretin-Based Therapy for the Management of Type 2 Diabetes
Kristin Gonzales & Adrian Vella

Part III Diagnosis and Management of Cardiovascular Risk Factors and Cardiovascular Disease

14 Screening asymptomatic patients with prediabetes and diabetes for cardiovascular disease

15 Choosing medications for type 2 diabetes – what weighting should be given to cardiovascular risk reduction?
Adrian Vella

16 Choosing Medications for Weight Loss in Type 2 Diabetes Mellitus
Shubhada Jagasia, Alexander J. Williams, Chase D. Hendrickson

17 Are statins the optimal therapy for cardiovascular risk in patients with diabetes? What newer agents are there for the treatment for dyslipidemia in diabetes? Are triglycerides an important risk factor for diabetes?
Recie Davern, Timothy O’Brien

18 New Agents for Treatment of Dyslipidemia
Vinaya Simha

19 Surgery for weight management
Silvana Obici and Judith Korner

20 Revascularization Strategies in Patients with Diabetes Mellitus and Ischemic Heart Disease
Madeline K. Mahowald, Chiam Leker Locker, Mandeep Singh, Robert L. Frye

Part IV Management of Disease Complications

21 Management of hyperglycemia in critical illness

22 Diagnosis and management of ophthalmic complications of diabetes

23 Upper Gastrointestinal Manifestations of Diabetes
Michael Camilleri

Index

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