Preface ix
List of Contributors xi
Part 1 Concerns in Pregnancy
1 Alcohol Use in Pregnancy and Lactation 3
Ruta M. Nonacs
2 Smoking, Vaping, and Nicotine Exposure 9
John Byrne and George Saade
3 Opioid Use, Misuse, and Addiction in Pregnancy and Postpartum 15
Mishka Terplan
4 Depression 21
Kimberly Yonkers
Part 2 Antenatal Testing
5 Prenatal Testing for Chromosomal Abnormalities 29
Mary E. Norton
6 Fetal Echocardiography 41
Joshua A. Copel
7 Clinical Use of Doppler 49
Henry L. Galan
8 Antepartum Testing 61
Michael P. Nageotte
9 Fetal Blood Sampling and Transfusion 69
Patricia Santiago‐Munoz
10 Preconception Genetic Screening 77
Lauren Sayres and Jeffrey A. Kuller
Part 3 Maternal Disease
11 Maternal Anemia 89
Elaine Duryea
12 Hemoglobinopathies in Pregnancy 97
Bradley Sipe and Judette Louis
13 Fetal and Neonatal Alloimmune Thrombocytopenia 105
Russell Miller and Richard Berkowitz
14 Rheumatological Disorders 113
Lisa R. Sammaritano and Bonnie L. Bermas
15 Antiphospholipid Syndrome 125
Robert M. Silver
16 Inherited Thrombophilias 131
Andra H. James and Jerome J. Federspiel
17 Valvular Heart Disease in Pregnancy 141
Blake Zwerling and Afshan B. Hameed
18 Peripartum Cardiomyopathy 165
Sarah Rae Easter and Carolyn M. Zelop
19 Thromboembolism 181
Michael J. Paidas
20 Renal Disease 201
Shivani Patel
21 Obesity 209
Patrick S. Ramsey
22 Diabetes Mellitus 219
Mark B. Landon and Steven G. Gabbe
23 Thyroid Disorders 231
Elizabeth O. Buschur and Stephen F. Thung
24 Hepatitis in Pregnancy 241
Andrew Myers, Asa Oxner, John Sinnott, and Christian Brechot
25 Asthma 253
Michael Schatz
26 Epilepsy 263
Thomas McElrath
27 Chronic Hypertension 273
Michal Fishel Bartal and Baha M. Sibai
28 Cytomegalovirus, Genital Herpes, Rubella, and Toxoplasmosis 285
Kerry E. Drury and Brenna L. Hughes
29 Syphilis 293
Emily H. Adhikari
30 Vector‐Borne Diseases in Pregnancy: Zika, West Nile, and Chagas Disease 301
Karin Nielsen‐Saines and Tara Kerin
31 Influenza 317
Amanda C. Zofkie and Vanessa Rogers
32 Malaria 323
Blair J. Wylie
33 Human Immunodeficiency Virus Infection 333
Emily H. Adhikari
34 Parvovirus B19 343
Kathy C. Matthews, Emilie L. Vander Haar, and Laura E. Riley
35 Group B Streptococcus 351
Caitlin A. MacGregor, and Mara J. Dinsmoor
36 Biliary, Liver, and Pancreatic Disease 361
Vic Velanovich, Elizabeth Hoover, and Stephanie Ros
Part 4 Obstetric Problems
37 Cervical Insufficiency 375
Rupsa C. Boelig and Vincenzo Berghella
38 Nausea and Vomiting 387
Jared T. Roeckner and Haywood L. Brown
39 Fetal Death and Stillbirth 397
Alexander M. Saucedo and Robert M. Silver
40 Abnormal Amniotic Fluid Volume 407
Christina M. Ackerman, Thomas R. Moore, and Heather S. Lipkind
41 Fetal Growth Restriction 421
Jodi S. Dashe and Anne M. Ambia
42 Rh and Other Blood Group Alloimmunizations 431
Kenneth J. Moise Jr
43 Preterm Labor 443
Hyagriv N. Simhan
44 Prevention of Preterm Birth 449
Anna King and Sarah J.E. Stock
45 Premature Rupture of the Membranes 461
Brian M. Mercer
46 Indicated Late‐Preterm and Early‐Term Deliveries 475
Catherine Y. Spong
47 Chorioamnionitis 481
Catalin S. Buhimschi and Irina A. Buhimschi
48 Third‐Trimester Bleeding 493
Ilina D. Pluym and Christina S. Han
49 Amniotic Fluid Embolism 507
Irene A. Stafford and Michael A. Belfort
50 Preeclampsia 517
Michal Fishel Bartal and Baha M. Sibai
Part 5 Labor and Delivery
51 Elective Induction of Labor 531
Rachel G. Sinkey
52 Electronic Fetal Heart Rate Monitoring 539
David A. Miller
53 Breech Delivery 555
G. Justus Hofmeyr, and Mercy‐Nkuba Nassali
54 Vaginal Birth After Cesarean 563
James R. Scott
55 Placenta Accreta Spectrum 571
Robert M. Silver and Deirdre J. Lyell
56 Shoulder Dystocia 581
George A. Macones and Robert B. Gherman
57 Twins, Triplets, and Beyond 587
Mary E. D’Alton
58 Postpartum Hemorrhage 601
David B. Nelson
Appendix A: Evaluation of Fetal Health and Defects 613
Lynn L. Simpson
Index 629
