Pharmacological Studies in Natural Oral Care

Edited by a natural product scientist, clinician, pharmacologist and a dental surgeon, the book helps oral care specialists to implement safe and effective natural medicine therapies to complement current practice guidelines.

With oral care specialists focusing their attention on the interdisciplinary connections between oral health, heart health, gastrointestinal health, etc., and with increasing antibiotic resistance and stronger antibiotics now reserved for serious active infection, the importance of herbal antibiotics is increasing exponentially. This book helps to implement safe and effective natural medicine therapies to complement the current practice guidelines.

Pharmacological Studies in Natural Oral Care is a comprehensive compilation and explores all the measures to utilize the natural oral care obtained from plants, animals, and mineral drugs for dental care. Herbal extracts are used in dentistry for reducing inflammation, as antimicrobial plaque agents, for preventing the release of histamine, and as antiseptics, antioxidants, antimicrobials, antifungals, antibacterials, antivirals and analgesics. They also aid in healing and are effective in controlling microbial plaque in gingivitis and periodontitis, thereby improving immunity.

Audience

This important new book will be invaluable to medicinal chemists, pharmacologists, natural product formulation scientists, dental surgeons, orthodontists, periodontists, endodontists, prosthodontists, maxillofacial surgeons, dentists, oral hygienists, as well as a reference for the pharmaceutical/ herbal industries and dental libraries.

Preface xxv

Part I: Phytopharmaceuticals in Various Diseases 1

1 Ayurvedic Approaches to Oral Health and Hygiene: A Review 3
Manindra Mohan Shrivastava, Prashant Kr. Gupta, Kamal Shah, Durgesh Nandini Chauhan and Nagendra Singh Chauhan

2 Emerging Role of Medicinal Plants in the Prevention of Oral Cavity Disorders 33
Navneet Kishore and Bhanu Pratap Singh

3 Natural Oral Care and Herbal Products for Oral Diseases and Oral Hygiene Maintenance 47
Goma Kathayat, Diane Isabel Selvido, Hans Erling Skallevold, Maan Bahadur Rokaya, Bishwa Prakash Bhattarai, Anand Marya and Dinesh Rokaya

4 Complementary and Alternative Medicine: Gains and Drawbacks with Special Reference to Oral Healthcare 61
Ezi Abigail Akaji

5 Nutraceutical Agents on Oral and Periodontal Health and Disease 83
Gaetano Isola, Alessandro Polizzi and Simona Santonocito

6 Role of Herbal Products as Denture Disinfectants and Cleansers 103
Jacob Mathew Philip, Helen Mary Abraham, Tamizhesai, M. Navin Bharathy, C.J. Venkatakrishnan, Saranya Varadarajan, Raghunathan Jagannathan and Thodur Madapusi Balaji

7 Use of Natural Oral Care Products in Orthodontics 125
Anand Marya, Mohmed Isaqali Karobari, Pravin Kumar Shah and Dinesh Rokaya

8 Herbs and Their Applications as Root Canal Medicaments 149
S. Balagopal, Vandana James, Nagarajan Geethapriya, Shekar Shobana, Saranya Varadarajan, Raghunathan Jagannathan and Thodur Madapusi Balaji

9 Herb-Derived Phytochemicals for Dental Implant Applications 167
Saranya Varadarajan, Narasimman Muthusamy, Nithiyarajan Nambirajan, Rathinavel Pandian Manickavel, C.J. Venkatakrishnan, Jimson Samson, Raghunathan Jagannathan, Thodur Madapusi Balaji, S. Lakshmi Priya and Swaminathan Rajendran

10 Natural Compounds in the Treatment of Oral Submucous Fibrosis 183
Urmi Ghone, Gargi Sarode and Sachin Sarode

11 The Effects of Natural Products on Mouth Sores 197
Marzie Boskabady, Sepide Behrouz, Mahla Mohammadi and Mohammad Hossein Boskabady

12 Natural Products to Cure Bad Breath 217
Khalid Mohammed Khan, Shehryar Hameed and Shahbaz Shamim

13 Herbal Formulations as Denture Cleansers 253
Amar Bhochhibhoya, Sahara Shrestha, Rejina Shrestha and Manjeev Guragain

14 Natural Oral Care Therapy for Peri-Implant Diseases 269
Bharat Mirchandani, Hans Erling Skallevold, Artak Heboyan, Diane Isabel Selvido, Viritpon Srimaneepong, Pasutha Thunyakitpisa and Dinesh Rokaya

15 Natural Compounds in the Treatment of Recurrent Aphthous Stomatitis 285
Gargi Sarode, Madhura Pawar, Vivek Pawar and Sachin Sarode

16 Alveolar Bone Protective Effects of Natural Products 299
Diane Isabel Selvido, Hans Erling Skallevold, Bishwa Prakash Bhattarai, Rajesh Dashaputra, Azeem UI Yaqin Syed and Dinesh Rokaya

17 Natural Oral Care Products for the Treatment of Stomatitis 311
Vivekanand Kattimani, Gnana Sarita Kumari Panga, Swetha Gnanavel, Deepeka Saravanan and Nagalaxmi Hymavathi Chintalapati

Part II: Plants and Phytoconstituents Used in Natural Oral Care 357

18 Cranberry and Oral Health 359
Kamal Shigli, Sushma S. Nayak, U. B. Bolmal and Kamal Shah

19 Mangroves: Potent Botanicals as Therapeutics for Oral Ailments 391
Merry Kashyap, Akshar Radhakrishnan, Priyanka Singh, Amrita Sinharay, Kavyasree Marabanahalli Yogendraiah and Santosh Anand

20 Tea Tree Oil on Oral Health -- A Systematic Review 403
Kalyana Chakravarthy Pentapati and Chenna Deepika

21 Oregano Oil and Grape Seed Oil -- A Potent Displacer of Commercially Available Denture Cleansers 425
Shetty Prajna P., Chowdhary Ramesh, Shetty Pooja P. and Volety Supraja

22 Punica granatum (Pomegranate): A Potential Herbal Medicine in Treating Periodontal Disease in the Modern World of Dentistry 435
Sumanth Gunupati, Sukrutha Biradavolu, Priyanka Nitin and Thummala Kalyani

23 Potential Effects of Schinus terebinthifolia Raddi (Anacardiaceae) for the Treatment of Oral Conditions 453
Ana Carolina Rivas, Nathalya Maria Vilela Moura and Mario Taba Jr.

24 Melatonin: A Naturally Derived Molecule as a Protector of Oral Health 467
Thodur Madapusi Balaji, Saranya Varadarajan, C.J. Venkatakrishnan, Raghunathan Jagannathan, Bhuvaneswari Birla Bose, Juala Catherine, Vignesh Vikram, T. Parthasarathi, S. Lakshmi Priya and Swaminathan Rajendran

25 Myrrha and Oral Health 485
Randa A. Alfotawi

26 Syzygium aromaticum -- Role in Oral Health and Dental Care 499
Vahid Reza Askari, Zohre Najafi and Vafa Baradaran Rahimi

27 Acemannan: A Promising Natural Polysaccharide in Dentistry 519
Hans Erling Skallevold, Dinesh Rokaya and Pasutha Thunyakitpisal

28 Piper betel Linn. (Betel Leaf) and Its Beneficial Effects in Orodental Ailments: A Memoir 539
Aditya Shetty, Princy Louis Palatty, Bharathi Shetty, Sembagalakshmi Thirunarayanan, Priyanka Latha Senthilkumar, Sharake Meera, Suresh Rao, Shamprasad Varija Raghu and Manjeshwar Shrinath Baliga

29 Aloe Vera and Oral Health: A Systematic Review 553
Kalyana Chakravarthy Pentapati, Hanan Siddiq and Abhinav T.N.

30 Cinnamomum zeylanicum -- A Review for Its Role in Oral Health and Dental Care 577
Vahid Reza Askari, Zohre Najafi and Vafa Baradaran Rahimi

31 Babool (Acacia nilotica) and Oral Health 597
Anupam Jaiswal, Megha Verma, Seema Kohli, Durgesh Nandini Chauhan, Kamal Shah and Nagendra Singh Chauhan

32 Applications of Andrographis paniculata and Its Constituents for Management of Oral Diseases 607
Ambili R., Nisha K.J., Biji Brigit K. and Rema J.

Part III: Advancement in Natural Product Oral Care 629

33 In Silico Approach with Phytochemical Analysis and Its Role in Oral Potentially Malignant Disorders (OPMD) and Oral Cancer 631
Vaibhav Sunil Ladke, Gitanjali Javir and Gauri M. Kumbhar

34 Anticancer Activities of Trigonella foenum-graecum L. and Trigonelline on an Oral Squamous Cell Carcinoma Cell Line 641
Saranya Varadarajan, Thodur Madapusi Balaji, Malathi Narasimhan, Durai Pandian Chamundeeswari Meenakshi and Dhanapal Sakthisekaran

35 Evaluation of The Anti-Inflammatory Action of Andiroba Oil -- Carapa guianensis aubl (Meliceae) in Oral Mucositis 651
Fabricio Mesquita Tuji, Priscilla Bittencourt de Almeida Figueiredo, Gabriel Henrique Soares Cavalcante and Rommel Mario Rodriguez Burbano

36 Trends of Clinical Studies with Xylitol or Propolis Toothpastes 669
Mariana Leonel Martins, Natália Magno Von Helde, Yuri Wanderley Cavalcanti, Lucianne Cople Maia and Andréa Fonseca-Gonçalves

37 Use of Polyols in Dentistry: Effects on Tooth Mineral Dynamics and Oral Biofilms 689
Igor Zen, Tamires Passadori Martins, Caio Sampaio, Alberto Carlos Botazzo Delbem, Douglas Roberto Monteiro and Juliano Pelim Pessan

38 Therapeutic Activity of Salvia officinalis L. Hydro-Ethanolic Extract from Aerial Parts on Dental Disease 703
Maryam Eidi and Reza Ghahramani

39 Effect of Black Pomegranate Hydro-Ethanolic Extract from Peel in Diabetic Male Rats with Candida albicans Oral Mucosa Infection 713
Maryam Eidi and Reza Ghahramani

40 In Vitro and In Vivo Efficacy of Phytoactive-Based Oral Care Regimens in the Prophylaxis of Oral Biofilm and Augmentation of Oral Hygiene 723
Arumugam Priya, Nagaiah Hari Prasath, Nambiraman Malligarjunan and Shunmugiah Karutha Pandian

41 Natural Oral Care Approach and Application in COVID-19 Management 775
Beuy Joob and Viroj Wiwanitkit

42 Fabricated Plant-Based Nanoformulations: Therapeutics for Oral Health 793
Santosh Anand and Prabhakar Mishra

Index 807

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