Put the world`s most well-known kidney reference to work in your practice with the 11th Edition of Brenner & Rector`s The Kidney. This two-volume masterwork provides expert, well-illustrated information on everything from basic science and pathophysiology to clinical best practices. Addressing current issues such as new therapies for cardiorenal syndrome, the increased importance of supportive or palliative care in advanced chronic kidney disease, increasing live kidney donation in transplants, and emerging discoveries in stem cell and kidney regeneration, this revised edition prepares you for any clinical challenge you may encounter.
Extensively updated chapters throughout, providing the latest scientific and clinical information from authorities in their respective fields.
Lifespan coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and old age.
Discussions of today`s hot topics, including the global increase in acute kidney injury, chronic kidney disease of unknown etiology, cardiovascular disease and renal disease, and global initiatives for alternatives in areas with limited facilities for dialysis or transplant.
New Key Points that represent either new findings or "pearls" of information that are not widely known or understood.
New Clinical Relevance boxes that highlight the information you must know during a patient visit, such as pertinent physiology or pathophysiology.
Hundreds of full-color, high-quality photographs as well as carefully chosen figures, algorithms, and tables that illustrate essential concepts, nuances of clinical presentation and technique, and clinical decision making.
A new editor who is a world-renowned expert in global health and nephrology care in underserved populations, Dr. Valerie A. Luyckx from University of Zürich.
Board review-style questions to help you prepare for certification or recertification.
Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
1. Embryology of the Kidney 2. Anatomy of the Kidney 3. The Renal Circulations and Glomerular Ultrafiltration 4. Glomerular Cell Biology 5. Metabolic Basis of Solute Transport 6. Transport of Sodium, Chloride, and Potassium 7. The Regulation of Calcium, Magnesium, and Phosphate Excretion by the Kidney 8. Renal Handling of Organic Solutes 9. Renal Acidification Mechanisms 10. Urine Concentration and Dilution and The Cell Biology of Vasopressin Action 11. Vasoactive Molecules and the Kidney 12. Aldosterone and Mineralocorticoid Receptors: Renal and Extrarenal Roles 13. Arachidonic Acid Metabolites and the Kidney 14. Disorders of Sodium Balance 15. Disorders of Water Balance 16. Disorders of Acid-Base Balance 17. Disorders of Potassium Balance 18. Disorders of Calcium, Magnesium, and Phosphate Balance 19. Epidemiology of Kidney Disease 20. Risk Prediction in Chronic Kidney Disease 21. Developmental Programming of Blood Pressure and Renal Function 22. Physiology and Pathophysiology of the Aging Kidney 23. Clinical Approach and Laboratory Assessment of the patient with kidney disease 24. Interpretation of Electrolyte and Acid-Base Parameters in Blood and Urine 25. Diagnostic Kidney Imaging 26. The Kidney Biopsy 27. Biomarkers in Acute and Chronic Kidney Diseases 28. Pathophysiology of Acute Kidney Injury 29. Prevention and Management of Acute Kidney Injury 30. Pathophysiology of Proteinuria 31. Primary Glomerular Disease 32. Secondary Glomerular Disease 33. Overview of Therapy for Glomerular Disease 34. Thrombotic Microangiopathy and Microvascular Disease 35. Tubulointerstitial Diseases 36. Urinary Tract Infection in Adults 37. Urinary Tract Obstruction 38. Urinary Stone Disease 39. Diabetic Nephropathy 40. Cardiorenal Syndromes 41. Kidney Cancer 42. Onco-Nephrology: Kidney Disease in Patients with Cancer 43. Inherited Disorders of the Glomerulus 44. Inherited Disorders of the Renal Tubule 45. Cystic Diseases of the Kidney 46. Primary and Secondary Hypertension 47. Renovascular Hypertension and Ischemic Nephropathy 48. Pregnancy and Kidney Disease 49. Antihypertensive Therapy 50. Diuretics 51. Mechanisms of Progression of Chronic Kidney Disease 52. The Pathophysiology of Uremia 53. Chronic Kidney Disease-Mineral Bone Disorder 54. Cardiovascular Aspects of Kidney Disease 55. Hematologic Aspects of Kidney Disease 56. Endocrine Aspects of Chronic Kidney Disease 57. Neurologic Aspects of Kidney Disease 58. Dermatologic Conditions in Kidney Disease 59. Staging and Management of Chronic Kidney Disease 60. Dietary Approaches to Kidney Diseases 61. Drug Dosing Considerations in Patients with Acute Kidney Injury and Chronic Kidney Disease 62. Supportive Care in Advanced Kidney Disease 63. Hemodialysis 64. Peritoneal Dialysis 65. Critical Care Nephrology 66. Plasmapheresis 67. Elimination Enhancement of Poisons 68. Interventional Nephrology 69. Transplantation Immunobiology 70. Clinical Management of the Adult Kidney Transplant Recipient 71. Considerations in Live Kidney Donation 72. Diseases of the Kidney and Urinary Tract in Children 73. Fluid, Electrolyte, and Acid-Base Disorders in Children 74. Renal Replacement Therapy (Dialysis and Transplantation) in Pediatric End-Stage Kidney Disease 75. Global Challenges and Initiatives in Kidney Health 76. Latin America 77. Africa 78. Near and Middle East 79. Indian Subcontinent 80. Far East 81. Oceania Region 82. Ethical Dilemmas Facing Nephrology: Past, Present, and Future 83. Health Disparities in Nephrology 84. Care of the Older Adult with Chronic Kidney Disease 85. Stem Cells, Kidney Regeneration, Gene and Cell Therapy in Nephrology